产品货号：
Z29226
中文名称：
TXNRD1抗体
英文名称：
Anti-TXNRD1 antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TXNRD1 antibody |
| 指标别名 | GRIM 12;GRIM12;KDRF;thioredoxin reductase 1;Thioredoxin reductase TR1;TR;TR1;TRXR1;TXNR;TXNRD1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM(Intracellular),Direct ELISA |
| 基因名称 | TXNRD1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human TXNRD1 recombinant protein (Position:L344-G649). |
| 实际分子量 | 55KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family,and is a member of the thioredoxin (Trx) system.Three thioredoxin reductase (TrxR) isozymes are found in mammals.TrxRs are selenocysteine-containing flavoenzymes,which reduce thioredoxins,as well as other substrates,and play a key role in redox homoeostasis.This gene encodes an ubiquitously expressed,cytosolic form of TrxR,which functions as a homodimer containing FAD,and selenocysteine (Sec) at the active site.Sec is encoded by UGA codon that normally signals translation termination.The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure,the Sec insertion sequence (SECIS) element,which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.Alternative splicing,primarily at the 5' end,results in transcript variants encoding same or different isoforms,including a glutaredoxin-containing isoform that is predominantly expressed in testis. |
| Uniprot ID | Q16881 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Flow Cytometry(Intracellular) 1～3μg/1×106 cells Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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